Metabolic maps and functions of the Plasmodium falciparum apicoplast
Stuart A. Ralph, Giel G. van Dooren, Ross F. Waller, Michael J. Crawford, Martin J. Fraunholz, Bernardo J. Foth, Christopher J. Tonkin, David S. Roos, Geoffrey I. McFadden
SUMMARY: Discovery of a relict chloroplast (the apicoplast) in malarial parasites presented new opportunities for drug development. The apicoplast — although no longer photosynthetic —
CONTEXT: ...of the malaria parasite's distant photosynthetic ancestry. Plastids are derived from the endosymbiosis of cyanobacteria, and the apicoplast is no exception. Importantly,...
Nature Reviews Microbiology 2, 203-216 (01 Mar 2004) Review
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